116EVALUATION OF ANTIDIABETIC POTENTIAL OF MARKETED POLYHERBAL FORMUALTION (AYURSLIM) ON HIGH FAT DIETSTREPTOZOTOCIN INDUCED OBESE DIABETIC RATSType-II diabetes mellitus became a common problem worldwide. Obesity is one of the leading causes for type-II diabetes. In the present study we investigated the poly herbal formulation Ayurslim (AS) for obesity associated diabetes in normal and high fat diet-STZ injected rats. Blood glucose, total cholesterol, triglycerides, serum LDL, HDL, VLDL, AST, ALT levels and body weight in obese diabetic rats were evaluated. Administration of AS for 15 days significantly lowered the elevated levels of blood glucose, total cholesterol, triglycerides, LDL, VLDL, AST, ALT, body weight and increased the levels of HDL. From this study it was suggested that AS possess antidiabetic and antihyperlipidemic action and might be a good candidate for obesity associated diabetes.lathaudayan94@gmail.comResearch342012Diabetes mellitus,Streptozotocin,Poly herbal formulation,AyurslimP. Latha,A. Srikanth, C.K. Ashok kumar,B. Geethanjali,S. Janaki Prasanna,M. Swathi,D.S. PriyankaDepartment of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.,Department of Pharmacology, Sree Vidyanikethan College of Pharmacy, Sree Sainath Nagar, Tirupati - 517-102, Andhra Pradesh, India.