125COMPARATIVE ANTIDIABETIC INVESTIGATION OF AYURVEDA POLY HERBAL FORMULATION’S, NISAMALAKI CHURNA TABLET (NCT) IN ALLOXAN – INDUCED DIABETIC RATSThe present work was executed to a comparison was made the antidiabetic activities of four different marketed ayurveda polyherbal formulation’s Nisamalaki churna tablet (NCT) in alloxan - induced diabetic rats. The formulation containing consists of the following plants Amla (Emblica officinalis) fruit powder and Turmeric (Curcuma longa) rhizome powder in a defined proportion. Alloxan was administered as a single dose (120mg/kg, b.wt) to induce diabetes. Administration of different formulations suspension of NCT (200mg/kg) for 14 days, to alloxan - induced diabetic rats. The fasting blood sugar levels in alloxan - induced diabetic rats were investigated. Oral administration of different formulations suspension NCT (200mg/kg) for 14 days exhibited a significant reduction in blood glucose in alloxan induced diabetic rats was compared with the standard drugs Glibenclamide (5mg/kg). The result suggests that all the manufacturing formulations of NCT having good co - relations between them in alloxan - induced diabetes rats. Finally it concludes daily routine life’s the people are including the turmeric and emblica in their food products means possible to maintain the blood glucose level and its lead to control diabetes mellitus in our country.kishorkpm2006@gmail.comResearch342012Nisamalaki churna tablet (NCT),Glibenclamide,Alloxan,Antidiabetic activityV. Kishor Kumar,P. Satheesh Kumar,P.K. Ahammed Basheer,K. Safvan,Shafeeq Paredath,Seena Chaliyath,R. Manivannan,K.G. LalithaDepartment of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Phytopharmacy & Phytomedicine, JKKMMRF’s - Annai JKK Sampoorani Ammal College of Pharmacy, B. Komarapalayam – 638 183, Namakkal, Tamil Nadu, India.,Department of Pharmaceutics,