132BIO-MIMETIC SYNTHESIS OF SILVER NANOPARTICLES AND EVALUATION OF ITS FREE RADICAL SCAVENGING ACTIVITYNanocrystalline silver particles have found tremendous applications in the field of diagnostics and therapeutics. In recent years plant mediated biological synthesis of nanoparticles is gaining importance due to its simplicity and ecofriendliness. In this study, the biosynthesis of silver nanoparticles was carried out using Piper nigrum fruit extract as reducing agent. Quantification of silver nanoparticle synthesis was done using U-V Spectrophotometer. The synthesized silver nanoparticles were characterized with Scanning electron microscopy (SEM). The in vitro antioxidant properties of the biosynthesized silver nanoparticles have been evaluated using the DPPH assay, and these nanoparticles were found to have significant antioxidant capacity and thus can be used as potential radical scavenger against deleterious damages caused by the free radicals.draparnacmc@gmail.comResearch342012Piper nigrum fruit extract,Nanocrystalline silver particlesAparna Mani,Seetha Lakshmi S,Gopal VDepartment of Pharmacology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai-600116.,Department of Pharmacology, Sri Ramachandra Medical College and Research Institute, Porur, Chennai-600116.,Department of Pharmacognosy, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, Indira Nagar, Puducherry-605006, India