271DETERMINATION OF BIOLOGICALLY ACTIVE CONSTITUENTS OF THE FRUITS OF CUCUMIS SATIVUS LINN. USING GC- MS ANALYSISThe plant Cucumis sativus (Fam.Cucurbitaceae) commonly known as “Mullu vellari” in Tamil, “Sakusa” in Sanskrit, “Kheera” in Hindi and “Cucumber” in English is reported to possess a number of medicinal values. The present investigation was carried out to determine the possible bioactive components of the ethanolic extract of the fruits of Cucumis sativus using GC-MS analysis. Seven compounds were identified by GC-MS analysis. The major phytoconstituents were 2,3-Dihydro-3,5- dihydroxy-6-methyl-4H-pyran-4-one (10.86 %), 5-(Hydroxyl methyl)-2-furancarboxaldehyde (64.69 %), 4-Hydroxy-3-methyl- 2-butenyl-acetate (3.08 %), 2-(2-Methylcyclohexylidene)-hydrazinecarboxamide (11.54 %),n-Hexadecanoic acid (2.95 %), 1,2- Benzenedicarboxylic acid-diisooctyl ester (6.88 %) which are possessing many biological activities. Hence this study creates a platform to screen many bioactive components to treat liver disorder.sgkmsu@yahoo.co.inResearch472013Cucumis sativus,GC-MS analysis,Bioactive components,Liver disorderGopalakrishnan S,Kalaiarasi TDepartment of Chemistry, Noorul Islam University, Kumaracoil-629180, K.K.District, Tamil Nadu, India., Department of Pharmaceutical Chemistry, Manonmaniam Sundaranar University, Tirunelveli-627012, Tamil Nadu, India.