358REVIEW ON NOVEL HEART DISORDER-THE FABRY DISEASEFabry disease is an x- linked lysosomal disorder which involves cardiac complications like LV, RV hypertrophy and valvular thickening. This disease also called the "angiokeratoma corporis diffusum universale". As this disease is the multiorgan system disorder it requires collaboration effort among cardiology, nephrology and neurology. The definitive diagnosis of fabry disease is the measurement of alpha galactosidase activity in principal WBC (or) in cultured skin fibroblasts using genetic testing. Generally this disorder is prevented by using the beta blockers and the anti-platelet therapy. A graphical abstract regarding fabry disease was shown in figure 1vvrao_pharma@yahoo.co.inResearch4122013Lysosomal disorder,Alpha galactosidase enzyme,Genetic testing,Cultured skin fibroblastsPoornachand Tadisetti,Sivasai Kunta,Vivek Reddy T,Venkata Rao VutlaDepartment of Pharmacy Practice Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.,Department of Pharmacy Practice Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.,Department of Pharmacy Practice Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India.,Department of Pharmaceutical Chemistry, Chalapathi Institute of Pharmaceutical Sciences, Guntur, Andhra Pradesh, India