536DIFFERENTIATION OF STEM CELLS INTO PANCREATIC β-CELLS: REGENERATIVE MEDICINE FOR DIABETESDiabetes mellitus is one of the major healthcare problems. Due to increase in occurrence of type I Diabetes and complications in the current therapies there is a need to find an alternative therapy. Type I Diabetes is a result of autoimmune destruction of insulin producing pancreatic beta cells. Thus, stem cell therapy which causes the replacement of those cells would be appropriate, using in-vitro and in-vivo cell reprogramming from different cell sources. To develop such therapy an understanding of the molecular mechanisms, transcriptional regulations and the signaling pathways during pancreas development and morphogenesis is required. This review describes briefly about the genetic program underlying mouse pancreas morphogenesis and new stem cell therapy developed for beta cell regeneration neelam013@yahoo.co.inResearch5122014Pancreas development,Diabetes,Pancreatic β-cells,regenerative medicineShaishavi Jansari,Nayan Devashri,Ankita Dhanani,Neelam ChauhanDepartment of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER) Ahmedabad,Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER) Ahmedabad,Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER) Ahmedabad,Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER) Ahmedabad