546PERSPECTIVES ON OFF LABEL DRUG USE OF MEDICINESUse of approved drugs for unapproved or unlabeled indications has become common practice in recent times. This off-label use of drugs although proves to be a useful tool in clinical practice, yet, it is associated with certain issues and challenges especially those concerned with safety and efficacy of the drug in a new (unapproved / unlabeled) condition. This article intends to review an overall perspective on the off-label prescribing of drugs in all areas of medicinedrshubhasinghal@gmail.comReview5122014Off label,Unapproved indication,Good Reprint Practices,UnlabelledShubha Singhal,Sumit Bansal Senior Resident, Department of Pharmacology, MAMC, New Delhi, India.,PG- III Year, Department of Anaesthesia, AIIMS, New Delhi, India.