643ANTIMICROBIAL ABILITY OF CANNABIS SATIVA LINN, CALOTROPIS PROCERA, AND CYNODON DACTYLONThe antimicrobial activity of plant extracts were evaluated with different antibiotics susceptible and resistant microorganisms such as Penicillin and ampicillin. The antimicrobial activity was checked using disc diffusion method. Plant extracts were prepared from Acetone, Butanol, double distilled water, Ethanol. Butanol leaf extract of Cannabis sativa linn showed significant antimicrobial activity against Escherichia coli giving zone of inhibition 18 mm. It was also found that Acetone, Ethanol and distilled water leaf extract of Cynodon dactylon showed significant antimicrobial activity against Staphylococcus aureus giving zone of inhibition of 17mmrajendrapavan007@gmail.comResearch672015Antimicrobial activity,Cannabis sativa linn, Calotropis procera,Cynodon dactylon,Zone of inhibitionRajan Kumar Dubey,Sazid Ahmad Champarani,Rishabh Gupta,Gorakhnath Chaudhary,Rajendra PavanDepartment of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, 202145, Uttar Pradesh, India.,Department of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, 202145, Uttar Pradesh, India.,Department of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, 202145, Uttar Pradesh, India.,Department of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, 202145, Uttar Pradesh, India.,Department of Biotechnology, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, 202145, Uttar Pradesh, India.