724THE DETERMINATION OF CHARACTERIZATION OF BIOCOMPATIBLE CARRIER IMPLANT MATERIALS TO BE USED IN CONTROLLED DRUG RELEASE SYSTEMBiomaterials with synthetic or natural origin, are materials that will be prepared in harmony with the surrounding tissues and placed to repair in biological environment. The studies for the development of biomaterials are intended to controlled drug release system that is used active in the pharmaceutical sector in recent years. Hydrogels are used as a supp ort material in controlled drug release system. These gels can swell without solve in the water, high hydrophilic, flexible, generally three-dimensional, high mechanic stability, porous and cross-linked structures. Principal targets of the works in biomedical medicine are minimizing the drug dose, leading dosing interval, improving the quality of patient's life by preventing side effects. Controlled release systems are the best-response systems to these expectations. Since it requires the work more than ten years to develop a drug and to take the patent, pharmaceutical companies prefere to lead lifetime and effectiveness of drugs instead of to develop new drug and develope controlled release formulations. With this observation it is proposed that to establish the most advantageous biomaterial can be used in release systems by characterization of pH EMA, Xanthan gam and p(HEMA-MMA) hydrogels used in the controlled release systems and with the comparison of the profilesdrhesnaural@gmail.comResearch722016Biomaterial,pHEMA,p(HEMA-MMA), Controlled release,Hydrogel,Swelling behaviorPinar Erdem,Hesna Ural Kayalik,Sema CetinKirikkale University, Faculty of Science and Literature, Department of Biology, Kirikkale, Turkey,Ufuk University, Vocational School of Health Services, Ankara, Turkey,Kirikkale University, Faculty of Science and Literature, Department of Biology, Kirikkale, Turkey