731ASSESSMENT OF DRUG-DRUG INTERACTIONS IN TREATMENT CHARTS OF HOSPITALIZEDPATIENTSDrug-drug interactions (DDIs) are common in drug therapy which can be avoidable and manageable if detected. Pharmacist plays an important role in identifying, resolving and preventing DDIs. A retrospective, observational study conducted in a tertiary care super speciality hospital, Rajahmundry, India from April to September 2015. The objective of the study was to assess the drug-drug interactions in treatment charts of hospitalized patients. Data of 95 patient’s treatment charts were collected and recorded in the patient profile form, which consists of demographic details, case history, medical history, laboratory details and treatment details. DDI’s were screened using Medscape, Micromedex, and Drugs.com. The age of patient’s age ranges from 12-80 years and the majority of the patients were 18-60 years. We found 72 DDI’s, major 33(45.30%), moderate 36(50.00%), minor 01(01.33%) and contraindicated 02(02.70%). The most common DDI’s pairs were ciprofloxacin-Ondansetron, Cefopodoxime proxetil-ranitidine, and Ondansetron-Tramadol. This signifies the necessity of pharmacist to manage DDI’s bjmahendra2003@gmail.comResearch732016Drug-drug interactions,ciprofloxacin-Ondansetron, Cefopodoxime proxetil-ranitidine,Ondansetron-TramadolMahendra Kumar Betur Jayappa,Mary Prasanna Kumari B, Arun Chand Roby Kanamala,Hussain SKDepartment of Pharmacy Practice, Vikas Institute of Pharmaceutical Sciences, Rajahmundry, Andhra Pradesh, India,Department of Pharmacy Practice, Vikas Institute of Pharmaceutical Sciences, Rajahmundry, Andhra Pradesh, India,Department of Pharmacy Practice, Vikas Institute of Pharmaceutical Sciences, Rajahmundry, Andhra Pradesh, India,Department of Pharmacy Practice, Vikas Institute of Pharmaceutical Sciences, Rajahmundry, Andhra Pradesh, India