<?xml version="1.0" encoding="UTF-8"?><Articles><Article><id>772</id><JournalTitle>ANTI-IMPLANTATION  AND  ANTIFERTILITY  ACTIVITY  OF  AZADIRCHTA  INDICA  TINCTURE  (AIT)  AND  AZADIRCHTA  INDICA 30 POTENCY (AI 30) IN FEMALE ALBINO RATS</JournalTitle><Abstract>Neem  has  been  extensively  used  in  ayurveda,  unani  and  homoeopathic  medicine  and  has  become  a 
cynosure of modern medicine.  The use of plants as  emmenagogues, abortifacients and as local contraceptives was 
well  known  to  the  ancient  physicians  of  India  as  is  evident  from  some  of  the  available  books,  monographs  and 
reviews. Therefore the present study to evaluate the Anti-implantation and Antifertility activity of  Azadirchta indica
tincture  (AIT)  and  Azadirchta  indica30  potency  (AI30)  in  female  albino  rats.  Thereafter,  the  female  rats  were 
randomly divided into four groups of six rats each thus: Vehicle control - 1% tween 80 at the dose level of 10 ml/kg; 
Ethinyloestradiol and levonorgestrel (Ovral L  â€“  Standard drug);  Azadirchta  indica  tincture suspended in Vehicle; 
Azadirchta  indica30  potency  daily  for  19  days  respectively.  On  day  20  of  gestation,  each  rat  was  laparatomised 
under high ether anaesthesia. The uterine horns were exteriorized and incised at the greater curvature of the horns. 
The latter were examined for sites of implantation and resorption. Number of corpora lutea of pregnancy, number of 
live foetuses as well as weights of the foetuses and placentae were also determined. The number of fetus appeared to 
decrease more with AI 30, which may suggest the AI 30 is more effective than that of AIT. All the fetus of treated 
rats  grew  up  normally  without  showing  any  physical  abnormality  indicating  that  the  AIT  and  AI30  is  not 
abortifacient and teratogenic in albino rats. Absence of toxicity and lethality at the dose administered justifies the 
safe nature of the AIT and AI30</Abstract><Email>nirmal.md@gmail.com</Email><articletype>Research</articletype><volume>8</volume><issue>1</issue><year>2017</year><keyword>Azadirchta indica tincture, Azadirchta indica30 potency,Anti-implantation, Antifertility activity</keyword><AUTHORS>G.Nirmal,Arun Nilkanthrao Bhasme</AUTHORS><afflication>Maharashtra University of Health Sciences, Nasik, Maharastra, India,Principal, SonajiraoKshirsagar Homoeopathic Medical College, Beed 431122, Maharastra, India</afflication></Article></Articles>