<?xml version="1.0" encoding="UTF-8"?><Articles><Article><id>786</id><JournalTitle>ANDROGEN RECEPTOR IN TRIPLE NEGATIVE BREAST CANCER</JournalTitle><Abstract>Though many recent developments have been provided in terms of breast cancer treatments and targeted therapy,
the incidence of breast cancer is increasing throughout the world and it is the leading cause of cancer death in females. The
most heterogeneous type of breast cancer is the triple negative breast cancer (TNBC), involving many subtypes and mixed
entities which differ in many aspects: histology, molecular markers, prognosis, treatment and patient outcomes. Triple
negative breast cancer is also the most aggressive type of breast cancer due to its lack of hormone receptors and HER2
amplification. Recent studies have demonstrated the implication of androgen receptor (AR) in prognosis and therapy of
TNBC although this has not yet been completely elucidated. The aim of this review is to provide an overview about TNBC
and to state androgen receptor role and its importance in therapy of breast cancer in the near future.</Abstract><Email>Petra_elhajj@hotmail.com</Email><articletype>Review</articletype><volume>8</volume><issue>3</issue><year>2017</year><keyword>Triple Negative Breast Cancer,Androgen Receptor,Luminal Androgen Receptor,Anti-Androgen,Prognosis,Therapy,Disease free survival</keyword><AUTHORS>Petra EL Hajj,Razan Jarjour,Fadi Nasr,Khaled Habib, Evelyne EL Helou,Mona Diab-Assaf</AUTHORS><afflication>Molecular Tumorigenesis and Anticancer Pharmacology, EDST, Lebanese University, Hadat, Lebanon.,Molecular Tumorigenesis and Anticancer Pharmacology, EDST, Lebanese University, Hadat, Lebanon.,Faculty of Medicine, Lebanese University, Hadat, Lebanon.,Specialized Medical Laboratory, Al-Mazraa, Beirut, Lebanon.,Hematology-Oncology Department, Lebanese Hospital University Medical Center, Beirut, Lebanon.,Molecular Tumorigenesis and Anticancer Pharmacology, EDST, Lebanese University, Hadat, Lebanon.</afflication></Article></Articles>