846TO STUDY THE BACTERIOLOGICAL PROFILE IN POST OPERATIVE WOUND INFECTIONIn surgical patients, infection is an important cause of morbidity and mortality. A prospective study to find the pattern of microorganisms responsible for post operative wound infections and their antibiotic susceptibility profile was therefore conducted. A 75 post operative wound cases were included thereby various potential bacterial pathogens isolated from 94 patients. Among them Staphylococcus aureus 33 (44%) predominated, followed by Escherchia coli 18 (24%), Klebsiella pneumonia 12 (16%), Pseudomonas aeruginosa 5 (6%), Proteus mirabilis 3 (4%), Serratia marcescens 2 (3%) Candida albicans 1 (1.5%) and other Enterobacteriaceae 1 (1.5%). Monomicrobial and Polymicrobial infection was observed in 60.8% and 39.2% patients respectively. Orthopedic surgery and Gastrointestinal surgery was associated with an increased risk of infection due to Methicillin resistant Staphylococcus aureus and Escherichia coli respectively. The quinolones, ciprofloxacin and ofloxacin, should be used as frontline drugs in the management of surgical wound infections at the hospital.nithish@gmail.comResearch1122020Nosocomial infections,Surgical Infection Society,Post Operative wound infection,MDR hospital floraNaveen Kumar Reddy DAssistant Professor of General Surgery, Melmaruvathur Adhiparasakthi Institute of Medical sciences and Research, Melmaruvathur, Tamilnadu, India.