902TO STUDY HCG AND CA-125LEVELS IN PREGNANCY AND ABORTION PATIENTSThe rate of fetal loss in clinically evident gestations has been reported to be approximately 10-15%. The rate will be obviously higher if we consider the preclinical losses diagnosed by ?- HCG levels starting 3 weeks following the last menstrual period.Maternal blood samples were taken in the first trimester and the serum was separated and measurement of hcg and CA-125 were done in the Central laboratory by using Enzyme Linked Immuno Sorbent Assay (ELISA).In the present study, it is necessary to mention that sample size is a limiting factor (20 participants in each group). But it should always be kept in mind that it is not possible to identify the cause of the recurrent early pregnancy loss in approximately half of the cases and this could be the limiting factor for any biochemical marker.The value of CA125 in recurrent abortions is still unclear and cannot be recommended on routine basis. On the other hand ?-HCG is highly sensitive as a single serum measurement for the prediction of pregnancy outcome.drpebyreddy@gmail.comResearch122010Menstrual period.CA-125, Amniotic fluid,Maternal blood samplesPulipati Saralamma,Prabhakar Reddy EAssociate Professor of Obstetrics and Gynecology, Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India.,Assistant Professor of Biochemistry, Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India.